In this amazing season premiere, who did Mike Delfino marry? The Bolens, Angie, her husband, Nick, and their 19-year-old son, Danny, have moved around a lot, but hope to settle down on Wisteria Lane now that real estate agent Lee has sold them Mary Alice's former house. Bree struggles to keep her affair with Karl away from Orson. Lynette's pregnancy is taking a toll on her and the love triangle between Susan, Mike and Katherine begins to heat up and takes another chapter.

Meanwhile, Ana is pushing the limits with Gabrielle, after the ending of the previous season finale. A pivotal female character gets strangled.